Biography

Alexandra V. Goldberg is a Clinical Scientist, Clinical Research Dietitian, and Clinical Trials Coordinator whose work bridges nutrition science, translational research, and hospital-based innovation. She holds a Master of Dietetics (First Class Honours) and is a Registered Dietitian with the New Zealand Dietitians Board (Reg. 20-02273). Her research and clinical practice focus on gastrointestinal physiology, metabolic health, early-life and respiratory-related nutrition, and the integrative mechanisms linking microbial ecology with immune function.

As a clinical scientist, Alexandra’s work centres on mechanistic understanding and clinical application. She has substantial expertise in managing complex gastrointestinal conditions, incorporating advanced assessment of feeding tolerance, gastric motility, and enteral nutrition responsiveness. Her contributions to device-based diagnostics— including SMāRT Tube research and Alimetry gastric mapping—reflect her commitment to precision phenotyping of GI dysfunction and to developing clinically actionable nutrition pathways for high-risk patients.

Alexandra’s research interests extend into developmental and respiratory immunity, particularly in populations characterised by heightened susceptibility to recurrent infections or immune dysregulation. Her work explores the microbiome–respiratory axis, focusing on how diet, microbial maturation, and metabolite dynamics influence airway resilience, mucosal immunity, and respiratory outcomes during vulnerable stages of life. She contributes to studies examining nutritional adequacy, microbial composition, micronutrient patterns, and early-life environmental factors that collectively shape host defense and respiratory tolerance. Her applied lens integrates molecular evidence with clinical pragmatism, ensuring interventions are both mechanistically grounded and feasible for real-world care.

Since joining Middlemore Clinical Trials in 2022, Alexandra has been involved in multiple Phase II and III clinical investigations in cardiometabolic disease and cardiovascular outcomes—including the VER-201-PH2-301 BELIEVE programme and the Synchronize CVOT trial. She provides methodological oversight in participant evaluation, protocol adherence, data fidelity, regulatory compliance, and endpoint interpretation, with a sustained emphasis on nutrition-relevant biomarkers and pathophysiological mechanisms. Her dual competency in clinical care and research execution enables her to operate at the interface of healthcare delivery and scientific inquiry.

Alexandra’s academic foundation includes rigorous training in medicinal chemistry, metabolism, and nutritional biochemistry. This interdisciplinary background informs her analysis of metabolic regulation, biochemical pathways, drug–nutrient interactions, and the scientific rationale for targeted nutrition strategies—particularly those addressing microbial development, immune modulation, and respiratory vulnerability. Her approach reflects a systems biology perspective, where nutrition serves as a regulatory component shaping metabolic, immunological, and microbial networks.

Clinically, Alexandra is highly regarded for her capability in designing and implementing advanced clinical nutrition interventions. She has supported adults and children across a spectrum of conditions—ranging from surgical recovery and chronic disease to recurrent respiratory illness, tolerance challenges, and developmental nutrition concerns. Her expertise in translating physiology, microbial science, and metabolic data into practical nutrition prescriptions allows her to deliver interventions that are both evidence-based and deeply individualised.

Alexandra’s work reflects a forward-looking vision for clinical nutrition as a scientific discipline—one that integrates mechanistic insights, translational research, and patient-centred care. Whether presenting at academic forums, contributing to multi-centre clinical trials, or shaping clinical nutrition strategies for vulnerable populations, she is recognised for her scientific precision, conceptual clarity, and commitment to advancing evidence-based healthcare.

Professional Roles & Affiliations

Alexandra contributes actively to New Zealand’s clinical nutrition and clinical research ecosystems, with roles spanning scientific investigation, clinical care, and translational methodology.

• Registered Dietitian – New Zealand Dietitians Board
  Practising under the Health Practitioners Competence Assurance Act 2003 (Reg. 20-02273), maintaining standards in clinical safety, cultural competence, and lifelong professional development.
• Clinical Scientist & Clinical Research Dietitian – Middlemore Clinical Trials
  Contributes to clinical trials across cardiometabolic, gastrointestinal, respiratory-related, and microbiome- oriented research, integrating nutrition endpoints with mechanistic and clinical outcomes.
• Clinical Trials Coordinator – Middlemore Clinical Trials
  Responsible for participant pathways, ethics and regulatory processes, GCP-aligned documentation, data integrity, and communication with international sponsors and CROs.
• Gastrointestinal Nutrition & Enteral Physiology Specialist
  Recognised for expertise in feeding tolerance, gastric motility interpretation (including Alimetry mapping), and advanced nutrition support for complex GI phenotypes.
• Member of Clinical Nutrition & Translational Research Networks
  Engages with regional hospitals and academic teams on initiatives exploring nutrition–microbiome–respiratory interactions, phenotyping resilience, and designing evidence-based nutrition interventions.

Training & Programme Development

Alexandra delivers scientific and clinical education to healthcare professionals, integrating mechanistic physiology, microbiome science, and applied nutrition into structured, research-aligned learning frameworks.

• Advanced Nutrition & Microbiome Pathways Training
  Focuses on gut–lung physiology, microbial modulation through diet, respiratory vulnerability, and the design of targeted nutrition interventions across life stages.
• Clinical Trials & Research Methodology Education
  Provides training on protocol design, informed consent, safety recognition, nutrition-related endpoints, translational data interpretation, and GCP documentation.
• Gastrointestinal & Enteral Nutrition Courses
  Covers gastric physiology, enteral feeding progression, diagnostic interpretation, and evidence-based nutrition strategies for high-complexity GI patients.
• Performance Physiology & Metabolic Nutrition Education
  Addresses energy periodisation, muscle physiology, metabolic adaptation, and behaviour-anchored lifestyle interventions for adults, adolescents, and active youth.
• Scientific Foundations of Supplementation & Formulation
  Integrates mechanisms of action, dose theory, quality standards, and nutrition–pharmacology interactions grounded in her chemistry and clinical science training.