Written by
Louise W Lu, PhD, MPH, BMLS
Written/Reviewed by
Alexandra V Goldberg, Registered Dietitian
Do you often feel dry, strained, or blurry-eyed during the day after staring at a computer, phone, or tablet for hours? And by nighttime, are your eyes tired, unfocused, or even slightly painful? If you think eye care just means “taking some lutein in the morning,” you may be missing your eyes’ most critical repair window — the overnight recovery phase before sleep.
☀️ During the day, they need defense against blue light, UV exposure, and oxidative stress.
🌙 At night, they enter a deep recovery phase — clearing waste and rebuilding retinal structure.
In this guide, we’ll break down a full-spectrum eye care strategy designed for high-intensity screen users — through ingredient structure, absorption timing, and bioactive synergy:
- Daytime use: NYO3® Lutein 40mg Eye Support Formula
- Nighttime use – Option 1: NYO3® Complex Lutein Bilberry Vision Softgels
- Nighttime use – Option 2: Health Life® Bilberry Plus Lutein 100s
- 1 fish oil capsule morning & night: High-Purity Fish Oil Collection (EPA:DHA = 3:2)
- 1 krill oil capsule morning & night: Superba Boost® Krill Oil Collection (≥56% Phospholipids)
Jump to Sections:
1｜Why Your Eyes Need Different Nutrients for Day and Night
Your eyes are not machines that operate at a constant pace around the clock. Their visual load, repair needs, and nutrient absorption vary dramatically depending on the time of day. Like a 24-hour relay race, your eyes go through a daytime “defense mode” and a nighttime “recovery mode.”
During the day, your eyes are constantly exposed to high-energy light—especially 400–500nm blue light from sunlight, screens, and LED lighting—which penetrates deep into the macula and creates oxidative stress.
Lutein acts as a natural “blue light filter” in the retina, absorbing this harmful light and reducing free radical buildup to preserve macular structure.
That’s why daytime defense calls for antioxidants like lutein, vitamins A, C, and E—to protect your eyes from photodamage and reduce fatigue.
During sleep, your eyes enter a restorative phase—retinal cells, neurons, and microvessels repair oxidative damage and rebuild structure.
In the macula, the fovea is rich in zeaxanthin to support central vision and dark adaptation, while the surrounding zones contain more lutein for broader antioxidant defense.
A 5:1 ratio of lutein to zeaxanthin mirrors this natural distribution, making it ideal for nighttime supplementation to enhance night vision clarity and central sharpness.
Fat-soluble antioxidants like astaxanthin and vitamin E are more efficiently delivered to the retina at night, while plant-based compounds like anthocyanins help improve nighttime circulation and reduce morning puffiness or blur.
During the day, digestion is more active, bile flow is steady, and meals typically contain fat—ideal conditions for absorbing fat-soluble nutrients like lutein, vitamin A, and E.
At night, improved blood flow, neuronal activity, and membrane renewal create optimal conditions for compounds like astaxanthin and bilberry extract to enter the retina’s repair pathways and integrate into tissue.
In short: when you take eye nutrients matters just as much as what you take.
2｜How Fish Oil + Krill Oil Complete the Picture for All-Day Eye Protection
About one-third of the fatty acids in the retina are DHA, which maintains membrane fluidity and supports sharp visual signaling.
EPA helps regulate inflammation and neural signaling, relieving eye fatigue, dryness, and irritation.
A daily ratio of EPA:DHA = 3:2 is ideal for balancing daytime protection and nighttime repair.
Unlike fish oil, the Omega-3s in krill oil are in phospholipid form, which integrates more efficiently into retinal cell membranes.
Its natural astaxanthin penetrates the blood-retina barrier, helping to reduce oxidative stress, screen-related fatigue, and morning puffiness.
Think of fish oil as the raw material and krill oil as the “courier” that delivers nutrients right where your eyes need them most.
Whether you're defending against blue light during the day or repairing retinal tissue at night, lipid support is essential.
Especially when taking fat-soluble nutrients like lutein and astaxanthin, without the right lipid carriers, absorption drops significantly.
We recommend taking 1 fish oil (EPA:DHA = 3:2) + 1 krill oil (≥56% phospholipids) both in the morning and at night—alongside your eye-protective formulas—to truly achieve “daytime defense + nighttime repair.”
It’s not just what you take for your eyes—but whether it’s properly supported by the right fats—that makes it work.
Final Thoughts｜Daily Usage Summary
Eye care isn’t something you do occasionally—it should follow your eye’s natural daily rhythm. Each morning, take one NYO3® Extra Strength Lutein 40mg softgel with breakfast, together with one fish oil and one krill oil to create a protective shield against blue light and oxidative stress. In the evening, take one NYO3® Complex Lutein Bilberry Softgel after dinner or before bed, along with one fish oil and one krill oil, to support retinal repair, circulation, and nighttime nerve regeneration. With this consistent “daytime defense + nighttime recovery + lipid support” strategy, you’re giving your eyes what they truly need to stay clear, comfortable, and resilient—24 hours a day.
